Red blood cell, shape abnormality, schistocyte | Keratocyte |
Also known as | Horn cell |
Definition | Fragmented red cell (a type of schistocyte) that has a pair of spicules separated by a semicircular concave segment of membrane. |
Ddx | Helmet cells |
Conditions associated with the shape abnormality | Thrombotic microangiopathy (TMA), macroangiopathic hemolytic anemia |
Mechanism of formation | Formed by rupture of pseudovacuoles, which arise from the fusion of two frayed membrane ends of damaged red cells. |
Source/author | William Aird |
Reviewed and edited by | Parul Bhargava |